Contribution of Calcium Channel Subtypes to the Intracellular Calcium Signal in Sensory Neurons
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چکیده
منابع مشابه
Calcium Channel Subtypes in Lamprey Sensory and Motor Neurons
El Manira, A. and N. Bussières. Calcium channel subtypes in different modulators require further study. Characterization lamprey sensory and motor neurons. J. Neurophysiol. 78: 1334– of the types and properties of calcium channels in identified 1340, 1997. Pharmacologically distinct calcium channels have spinal cord neurons is necessary to provide insight into their been characterized in dissoc...
متن کاملCalcium channel subtypes in lamprey sensory and motor neurons.
Pharmacologically distinct calcium channels have been characterized in dissociated cutaneous sensory neurons and motoneurons of the larval lamprey spinal cord. To enable cell identification, sensory dorsal cells and motoneurons were selectively labeled with fluorescein-coupled dextran amine in the intact spinal cord in vitro before dissociation. Calcium channels present in sensory dorsal cells,...
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BACKGROUND The cellular mechanisms of neuropathic pain are inadequately understood. Previous investigations have revealed disrupted Ca signaling in primary sensory neurons after injury. The authors examined the effect of injury on intracellular Ca stores of the endoplasmic reticulum, which critically regulate the Ca signal and neuronal function. METHODS Intracellular Ca levels were measured w...
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Multiple subtypes of voltage-gated calcium channels are differentially localized in brain neurons suggesting that they serve distinct roles in neuronal excitation and signaling. In organotypic hippocampal slice cultures, class D (L-type) calcium channels are predominantly located in the cell bodies of CA3 neurons while class B (N-type) and class A (P or Q-type) are localized in dendrites and as...
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Cadmium block of calcium channels was studied in chicken dorsal root ganglion cells by a whole-cell patch clamp that provides high time resolution. Barium ion was the current carrier, and the channel type studied had a high threshold of activation and fast deactivation (type FD). Block of these channels by 20 microM external Cd2+ is voltage dependent. Cd2+ ions can be cleared from blocked chann...
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ژورنال
عنوان ژورنال: Anesthesiology
سال: 2007
ISSN: 0003-3022
DOI: 10.1097/01.anes.0000267511.21864.93